Lead poisoning: acute exposure of the heart to lead ions promotes changes in cardiac function and Cav1.2 ion channels
نویسندگان
چکیده
منابع مشابه
Assessment of exposure to lead through air and biological monitoring in a lead and zinc mine
Background and aim: Lead is ubiquitous and one of the earliest metals discovered by the human. This metal is widely used in different industries due to its important physico-chemical properties like softness, high malleability, ductility, low melting point and resistance to corrosion. Lead absorbed in body with several routs and when transfer in blood is primarily in red blood cells. Human exp...
متن کاملEffects of Low Level of Lead Exposure on Responsiveness of The Rat Isolated Heart to Adrenergics
Background: There are controversial reports about the exact mechanisms of lead-induced hypertension, but many factors such as alteration in the responsiveness of cardiovascular system to endogenous substances including catecholamines could be one of the mechanisms involved. In present study, the effect of exposure to 100 ppm lead acetate by drinking water (in the periods of 4, 8 and 12 weeks)...
متن کاملApproach to Occupational Cases of Lead Poisoning
Introduction: Lead is a toxic metal that is found in the earth's crust and has been used by humans since 7000 years ago due to its density, malleability, high resistance and low melting point. The wide use of this metal in the industry, in addition to the exposure of workers, has led to widespread environmental pollution and public health problems in many parts of the world. Due to the widespre...
متن کاملDeaths from acute lead poisoning.
Alexander, F. W., and Delves, H. T. (1972). Archives of Disease in Childhood, 47, 446. Deaths from acute lead poisoning. The three fatal cases of acute lead poisoning described show the difficulty experienced in reaching an early diagnosis of lead intoxication. A rapid micromethod is now available for the determination of whole blood lead levels on small samples of blood, using atomic absorptio...
متن کاملAcute lead poisoning associated with backyard lead smelting in Jamaica.
Long-term backyard smelting of lead in a district known as Mona Commons, Kingston, Jamaica, has produced lead burdens as high as 30 000 mg/kg in soils near to the smelter, and indoor dust loadings of 373 microg/f2 in the residents' home. The blood lead levels (BPb) of 107 children from the district were in the range 2.2-202 microg/dL. Fifty-nine per cent of these had BPb levels above 10 microg/...
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ژورنال
عنوان ژورنال: Biophysical Reviews
سال: 2017
ISSN: 1867-2450,1867-2469
DOI: 10.1007/s12551-017-0303-5